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@broadinstitute @COBA-NIH @uhlmanngroup @ciminilab

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AKMHamid/README.md

Hi, I'm Kamal 👾

I'm a computational biologist with a background in experimental physiology, combining biomedical research with method development for bioimage analysis, spatial omics, and multimodal representation learning.

I am especially interested in developing deep learning models to answer biological questions, supported by reproducible analysis and benchmarking infrastructure for rigorous evaluation and biological interpretation.

Selected work

BenchRep — benchmarking representation learning for microscopy

An early-stage Python framework for reproducible benchmarking of microscopy representation-learning models, supporting both config-driven and programmatic workflows for training, prediction, evaluation, and provenance tracking.

VSTE — Variational Spatial Transcriptomics Encoder

A spatial-transcriptomics study and accompanying analysis repository evaluating VAE embeddings, downstream multimodal integration and clustering strategies, and classical CellProfiler image features for MERFISH-based cell-type deconvolution with DAPI and membrane imaging.

Associated publication: Evaluating integrative strategies for incorporating phenotypic features in spatial transcriptomics

sqY2H — screen quantification for composite plate images

An end-to-end image-analysis workflow I developed for registering composite yeast two-hybrid plate images, fitting well grids, segmenting and assigning colonies, and exporting continuous per-well growth measurements with quality-control and validation outputs.

Associated preprint: A scalable approach to resolving variants of uncertain significance

Outside science

Offline, my non-scientific obsessions include chasing better hi-fi headphones and IEMs, biking in circles on gravel, hunting for movies I somehow missed, revisiting Star Trek, and negotiating with reality for more high-fantasy reading time — all while answering to my feline overlords: James Clerk Maxwell and ReLU 🐈.

Pinned Loading

  1. uhlmanngroup/BenchRep uhlmanngroup/BenchRep Public

    Python framework for benchmarking representation learning models

    Python 1

  2. ciminilab/2026_Moser_Hamid_JMic ciminilab/2026_Moser_Hamid_JMic Public

    Jupyter Notebook 1

  3. ciminilab/sqy2h-screen-quantification ciminilab/sqy2h-screen-quantification Public

    Image-analysis workflow for composite plate registration, grid fitting, and colony segmentation and quantification in semi-quantitative yeast-2-hybrid screens.

    Jupyter Notebook

  4. QanvasLab QanvasLab Public

    QanvasLab Microscopy Figure Builder, an ImageJ/FIJI macro

    ImageJ Macro 3

  5. nag-cli nag-cli Public

    Minimal nagging sticky note terminal tool

    Shell

  6. FACrystalQuantMacro FACrystalQuantMacro Public

    ImageJ Macro